Prenatal exposure to the Great Chinese Famine and mid-age hypertension
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چکیده
منابع مشابه
Prenatal exposure to the Great Chinese Famine and mid-age hypertension
BACKGROUND One of the most terrible famines last century was Great Chinese Famine (GCF) in 1959~1961 when millions of people died from starving. Under-nutrition during famine between the Western and Eastern (Dutch Hungry vs. GCF) was similar, while cardiovascular consequences might not be the same. Addressing such questions may gain new insight into prevention of cardiovascular diseases. METH...
متن کاملPrenatal famine exposure and cognition at age 59 years.
BACKGROUND Despite the perceived importance of early life nutrition for mental development, few studies have related gestational undernutrition to later-life cognitive functioning. We investigated the consequences of gestational exposure to the Dutch famine of 1944-45 for cognitive functioning at the age of 59 years. METHODS We recruited men and women who were (i) born in birth clinics in Ams...
متن کاملImpact of Fetal and Infant Exposure to the Chinese Great Famine on the Risk of Hypertension in Adulthood
BACKGROUND Famine provides quasi-experimental conditions for testing the hypothesis of "programming" health effects by poor nutrition in early life. It remains uncertain whether early life exposure to famine increases the risk of hypertension in adulthood. There is a lack of data on the relative impact of exposure to famine during fetal development versus infancy (<2 years postnatal). We sought...
متن کاملRates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961.
CONTEXT Schizophrenia is a common major mental disorder. Intrauterine nutritional deficiency may increase the risk of schizophrenia. The main evidence comes from studies of the 1944-1945 Dutch Hunger Winter when a sharp and time-limited decline in food intake occurred. The most exposed cohort conceived during the famine showed a 2-fold increased risk of schizophrenia. OBJECTIVE To determine w...
متن کاملTransgenerational effects of prenatal exposure to the Dutch famine.
OBJECTIVE Maternal undernutrition during gestation is associated with increased metabolic and cardiovascular disease in the offspring. We investigated whether these effects may persist in subsequent generations. DESIGN Historical cohort study. SETTING Interview during a clinic or home visit or by telephone. POPULATION Men and women born in the Wilhelmina Gasthuis in Amsterdam between Nove...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0176413